Antifertility effects and dominant lethal assays for mutagenic effects of DEHP.
نویسندگان
چکیده
منابع مشابه
Antifertility effects and dominant lethal assays for mutagenic effects of DEHP.
Results of past animal studies have indicated the antifertility effects of phthalate esters and additional studies have suggested the potential mutagenic effects at very high doses. A toxicity study in mice has also been conducted in which chronic LD50 values were calculated for a group of phthalate esters. For DEHP, for example, the acute LD50 was 38.35 ml/kg, but after 10 weeks the value fell...
متن کاملStatistical considerations for dominant lethal mutagenic trials.
Statistics can be used in a biological assay as either a method of checking on the validity of conclusions or as a guide to the interpretation of experimental results. The division is sometimes made as one between hypothesis testing and estimation. However, the tool of hypothesis testing can be used as an interpretive aid in conjunction with the tools of estimation, so I prefer to make the divi...
متن کاملLethal and mutagenic effects of ultraviolet radiation on Glomerella conidia.
IN comparative studies of the mutagenic action of ionizing and ultraviolet radiation on conidia of the fungus Glomerella (5) it was evident that the shape of the mutation curve was different for the two types of radiation. The dose-mutation curve for the surviving spores was essentially linear for the ionizing radiations, but with the ultraviolet radiation the mutation curve rose with increasin...
متن کاملLethal and mutagenic effects of 5-iodouracil on bacteriophage T4td8rII.
Evidence was obtained which indicates that the lethal effect of 5-iodouracil (IUra) on bacteriophage T4 is not due to a mutagenic process. T4td8rII (thymine requiring, rapid lysis) double mutants were constructed. Reversion of T4td8rII to r(+) was measured. First, reversion by growth in the presence of the structural analogues chlorouracil (ClUra) and bromouracil (BrUra) did not correlate with ...
متن کاملthe effects of planning on accuracy and complexity of iranian efl students’ written narrative task performance
this study compared the different effects of form-focused guided planning vs. meaning-focused guided planning on iranian pre-intermediate students’ task performance. the study lasted for three weeks and concentrated on eight english structures. forty five pre-intermediate iranian students were randomly assigned to three groups of guided planning focus-on-form group (gpfg), guided planning focus...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1982
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.8245115